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KMID : 1197720080010010006
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대한파킨슨병 및 이상운동질환 학회지
2008 Volume.1 No. 1 p.6 ~ p.12
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Transcranial Sonography in Parkinson’s Disease and Parkinsonism
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Lee Won-Yong
Kim Sung-Tae
Kim Ji-Youn
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Abstract
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Transcranial sonography (TCS) is potentially useful for the diagnosis of Parkinson’s disease (PD). It is attractive because it is non-invasive, easily accessible and low risk test. So far, up to twenties of TCS studies in Parkinson’s disease and parkinsonism have been reported. However, studies on TCS have been restricted to European populations and no such study has been performed in Asian especially Korean population. To investigate the efficacy of TCS in Korean PD patients and its correlation with the clinical features, we carried out midbrain TCS in PD patients and normal controls, and evaluated the area of the substantia nigra (SN) hyperechogenicity and its ratio to the area of the whole m idbrain. According to our study, we could conclude that midbrain TCS is an effective diagnostic tool for detecting PD in the Korean population. In this review, we additionally summarized clinical application of TCS in differential diagnosis of atypical parkinsonism as well as restless leg syndrome and depression.
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KEYWORD
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Parkinson’s disease, Transcranial sonography, Substantia nigra
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